Expansion of CD56+ NK T and γδ T cells from cord blood of human neonates
| Autor: | Katsuyoshi Hatakeyama, Satoshi Yamagiwa, Satoshi Sugahara, Toshiyuki Koya, Yuhei Yoshida, Toru Abo, Hiroshi Watanabe, Nobuyuki Musha |
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| Rok vydání: | 1998 |
| Předmět: |
Adult
Cytotoxicity Immunologic T cell Immunology chemical and pharmacologic phenomena Biology Lymphocyte Activation Natural killer cell Interleukin 21 CD57 Antigens T-Lymphocyte Subsets medicine Humans Immunology and Allergy Cytotoxic T cell Cells Cultured Interleukin 3 Age Factors Infant Newborn CD28 Receptors Antigen T-Cell gamma-delta hemic and immune systems Fetal Blood Natural killer T cell CD56 Antigen Killer Cells Natural medicine.anatomical_structure Interleukin 12 Interleukin-2 Original Article |
| Zdroj: | Clinical and Experimental Immunology. 113:220-228 |
| ISSN: | 1365-2249 0009-9104 |
| DOI: | 10.1046/j.1365-2249.1998.00645.x |
| Popis: | SUMMARYA particular T cell population expressing NK cell markers, CD56 and CD57, exists in humans. Many CD56+ T and CD57+ T cells (i.e. NK T cells) exist in the liver and increase in number in the blood with ageing. They may be a human counterpart of extrathymic T cells, similar to NK1.1+ CD3int cells seen in mice. We investigate here the existence of such NK T cells in human cord blood and the in vitro expansion of these cells by the stimulation of human recombinant IL-2 (rIL-2). There were very small populations ( |
| Databáze: | OpenAIRE |
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