Phosphate disturbance in critically ill children: Incidence, associated risk factors and clinical outcomes
| Autor: | Ibrahim Abd El Naby Gad Ahmed, Eman G. Behiry, Doaa R. Soliman, Ahmed Nabih El Shazly, Effat H Assar |
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| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Hypophosphatemia medicine.medical_treatment Sepsis 03 medical and health sciences 0302 clinical medicine Internal medicine medicine 030212 general & internal medicine Intensive care medicine Original Research Mechanical ventilation Pediatric intensive care unit business.industry Incidence (epidemiology) Malnutrition Organ dysfunction nutritional and metabolic diseases Furosemide Phosphorus 030208 emergency & critical care medicine General Medicine medicine.disease stomatognathic diseases Surgery medicine.symptom Critical illness business medicine.drug |
| Zdroj: | Annals of Medicine and Surgery |
| ISSN: | 2049-0801 |
| Popis: | Background Hypophosphatemia is one of the common disorders that develop in critically ill patients. It has potential complications and is often unrecognized in those patients. Objective Determining the incidence of hypophosphatemia in critically ill children, its association with clinical outcomes and the possible risk factors. Methods 50 patients were enrolled in the study. Levels of serum phosphate were measured on day 1 and day 7 of PICU (Pediatric intensive care unit) stay. The following variables were analyzed: age, gender, diagnosis on admission, malnutrition, phosphorus intake, clinical severity score on admission OFI (Organ Failure Index) and daily scores PELOD (Pediatric Logistic Organ Dysfunction), sepsis, use of dopamine, furosemide and steroids and assessment of nutrition by z scores. Results The incidence of hypophosphatemia on admission was 42%. On seventh day of admission incidence of hypophosphatemia was 62%. Malnutrition was present in 24% of patients, serum phosphorus level was significantly lower in malnourished than in well-nourished children (p value = 0.018). Hypophosphatemia was associated with prolonged PICU length of stay (p Highlights • Hypophosphatemia was common in the first 7 days of pediatric intensive care unit hospitalization. • Significant association between hypophosphatemia and duration of use of mechanical ventilation. • Hypophosphatemia was associated with prolonged pediatric intensive care unit length of stay. • Hypophosphatemia was associated with use of furosemide, dopamine, steroid and β2 agonist. • Good nutrition of critically ill children has an important role in improving their clinical condition. |
| Databáze: | OpenAIRE |
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