Prognostic value of liver biochemical parameters for COVID-19 mortality

Autor:	Lin Ye, Furong Zeng, Jiling Zeng, Bin Chen, Guangtong Deng, Yuhao Deng, Yi Yang, Yitong Wang
Rok vydání:	2021
Předmět:	A/G ALB-to-GLB ratio ALP Alkaline phosphatase Specialties of internal medicine Cochrane Library Global Health Gastroenterology chemistry.chemical_compound 0302 clinical medicine NOS Newcastle-Ottawa Scale Medicine COVID-19 Coronavirus disease 2019 biology WMD Weighted mean difference SMD Standard mean difference Alanine Transaminase TBIL Total bilirubin General Medicine Prognosis Meta-analysis Survival Rate RC581-951 ALB Albumin Liver biochemical parameters 030220 oncology & carcinogenesis Original Article 030211 gastroenterology & hepatology AST Aspartate aminotransferase PRISMA Preferred Reporting Items for Systematic Reviews and Meta-Analyses TMPRSS2 Transmembrane serine protease 2 medicine.medical_specialty Coronavirus disease 2019 (COVID-19) Bilirubin DBIL Direct bilirubin GLB Globulin GGT Gamma-glutamyl transpeptidase 03 medical and health sciences ACE2 Angiotensin-converting enzyme 2 Internal medicine Humans Aspartate Aminotransferases Mortality Pandemics SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 ALT Alanine transaminase Hepatology CI Confidence interval SARS-CoV-2 business.industry Albumin COVID-19 IQR Interquartile range Publication bias chemistry Alanine transaminase biology.protein LDH Lactic dehydrogenase OR Odd risk business Biomarkers TBIL
Zdroj:	Annals of Hepatology Annals of Hepatology, Vol 21, Iss, Pp 100279-(2021)
ISSN:	1665-2681
DOI:	10.1016/j.aohep.2020.10.007
Popis:	Introduction: Coronavirus disease 2019 (COVID-19) has brought great challenges to global public health. However, a comprehensive analysis of the relationship between liver biochemical parameters and COVID-19 mortality is quite limited. Methods: We searched the following electronic databases: PubMed, Embase, Cochrane Library, Web of Science, Scopus, Wanfang and China National Knowledge Infrastructure database until May 5, 2020. STATA software was used for the statistical analyses. Results: A total of 25 studies involving 5971 COVID-19 patients were included in our analysis. Compared with non-survivors, survivors had lower levels of aspartate aminotransferase (AST) (weighted mean difference [WMD] = −16.71 U/L, 95%CI = [−21.03, −12.40], P
Databáze:	OpenAIRE
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