ANDROGEN RECEPTORS AS A FACTOR OF PROGNOSIS IN VARIOUS MOLECULAR-BIOLOGICAL SUBTYPES OF BREAST CANCER
Autor: | I. K. Vorotnikov, Denis A. Ryabchikov, Nikolai A. Kozlov, N. V. Chkhikvadze |
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Rok vydání: | 2017 |
Předmět: |
0301 basic medicine
Oncology Cancer Research medicine.medical_specialty business.industry Neoplasms. Tumors. Oncology. Including cancer and carcinogens molecular subtype medicine.disease factor prognosis Androgen receptor 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Breast cancer androgen receptor 030220 oncology & carcinogenesis Internal medicine medicine breast сancer skin and connective tissue diseases business RC254-282 |
Zdroj: | Sibirskij Onkologičeskij Žurnal, Vol 16, Iss 3, Pp 40-45 (2017) |
ISSN: | 2312-3168 1814-4861 |
Popis: | In the literature there has been increased interest in the study of androgenetic receptors (AR) in different molecular subtypes of breast cancer (BC) but we haven’t found consensus about the role of levels of androgens and their metabolites in samples of biological fluids for the development of breast cancer. Determination of the level of androgenetic receptors in the tumor in patients with breast cancer is very relevant and promising direction in the study of the prognosis of the disease and the search for new complementary approaches to endocrine therapy of breast cancer, especially when basal-like molecular subtype. |
Databáze: | OpenAIRE |
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