Prevalence of high IgM anticardiolipins in patients with ischemic stroke
| Autor: | A. Gardas, Alicja Bauer, J Majkowski, E Cieslak, M. Szczepański |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
medicine.medical_specialty
Lupus anticoagulant biology business.industry Lipoprotein(a) medicine.disease Gastroenterology Isotype Neurology Internal medicine Immunology Ischemic stroke biology.protein medicine cardiovascular diseases Neurology (clinical) Activated protein C resistance business Stroke Protein C medicine.drug Lipoprotein |
| Zdroj: | European journal of neurology. 5(3) |
| ISSN: | 1468-1331 |
| Popis: | Lupus anticoagulant (LA), IgG and IgM isotypes of anticardiolipins (aCL), lipoprotein (a), and the resistance to activated protein C were determined in patients with ischemic stroke. The raised concentration of the aCL-IgM isotype was noted in 42% of patients with this type of stroke, and it was in contrast with an 8% frequency of an increased level of aCL-IgG isotype in these cases. The high level of lipoprotein (a) was found with similar frequency in stroke patients and in age-matched control subjects. It is concluded that the elevated concentration of IgM isotype of anticardiolipin antibodies can be regarded as significant in the ethiological work-up in elderly stroke patients.Copyright Lippincott-Raven Publishers |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text