A randomized study showing improved skin quality and aesthetic appearance of dorsal hands after hyaluronic acid gel treatment in a Chinese population
| Autor: | Ruiyan Wang, Yan Wu, Shaomin Zhong, Wenyu Wu, Yan Tian, Jinhua Xu |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Dorsum
Adult China Esthetics Dentistry Dermatology Cosmetic Techniques Injectable Articles law.invention 030207 dermatology & venereal diseases 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Randomized controlled trial law Hyaluronic acid hyaluronic acid skin quality Medicine Humans Adverse effect Aged Chinese population Chinese business.industry Incidence (epidemiology) Restylane skinboosters Original Contribution Hand Skin Aging chemistry Patient Satisfaction 030220 oncology & carcinogenesis hand rejuvenation Dorsal hand business Skin elasticity |
| Zdroj: | Journal of Cosmetic Dermatology |
| ISSN: | 1473-2165 1473-2130 |
| Popis: | Background Patients are increasingly aware of the aesthetic appearance of aging hands. Aims To evaluate efficacy and safety of a hyaluronic acid gel for improving skin quality in aged skin of the dorsal hand. Methods This was a 15‐month randomized, multi‐center, evaluator‐blinded, split‐hand, no treatment‐controlled study. Three treatments with hyaluronic acid gel were administered in the same hand in adult Chinese subjects with grade 2 or 3 (mild or moderate aging) on the Hand Grading Scale (HGS). The primary objective was to evaluate the difference at 3 months between treated and untreated hands, based on the blinded evaluator's HGS assessment. Secondary assessments included the Global Aesthetic Improvement Scale (GAIS), biophysical measurements (skin elasticity, skin roughness and hydration), and subject satisfaction. Safety was evaluated by incidence of adverse events. Results A total of 100 subjects were enrolled. Clinically relevant differences in HGS favored HA gel (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|