Role of diffusion weighted MR imaging in characterization of focal kidney and upper urinary tract lesions
| Autor: | Tarek Abd El Moneim El-Diasty, Magdy Settein, Galal El Sayed Magdy El Hawary, Mohamed Salah Ebrahim Tantawy, Shereen ElShaer, Donia M. Sobh, Mohamed Abou El Ghar |
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| Rok vydání: | 2016 |
| Předmět: |
lcsh:Medical physics. Medical radiology. Nuclear medicine
medicine.medical_specialty lcsh:R895-920 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine medicine Effective diffusion coefficient Radiology Nuclear Medicine and imaging Diffusion-Weighted MR Imaging Diffusion weighted MRI Upper urinary tract Kidney Receiver operating characteristic business.industry medicine.disease RCC TCC body regions Clear cell renal cell carcinoma medicine.anatomical_structure ADC Radiology Nuclear Medicine and imaging 030220 oncology & carcinogenesis Renal mass Radiology Nuclear medicine business Clear cell Diffusion MRI |
| Zdroj: | The Egyptian Journal of Radiology and Nuclear Medicine, Vol 47, Iss 4, Pp 1689-1700 (2016) |
| ISSN: | 0378-603X |
| DOI: | 10.1016/j.ejrnm.2016.09.006 |
| Popis: | Previous studies suggested that the apparent diffusion coefficient (ADC) value could help in the differentiation and characterization of the benign and malignant renal masses.However, there is still wide overlap in the ADC values between the benign and malignant tumors. Objectives: To retrospectively assess the usefulness of the diffusion weighted imaging (DWI) for the characterization and differentiation between benign and malignant renal masses. Methods: A total of 87 renal and/or upper ureteric masses were included in our study. The signal intensity of the lesions was assessed on both the DWI and ADC map and the ADC value was calculated. t test, ANOVA test and Receiver operating characteristic (ROC) curve analysis were performed. Results: The ADC values of benign lesions were significantly higher than those of the malignant masses [3.2 versus 1.3 × 10−3 mm2/s], Median, P < 0.0001.The sensitivity and specificity of the DWI for the differentiation of benign and malignant masses were 98% and 73% using an ADC cutoffvalue of 2.2. Clear cell renal cell carcinoma demonstrates higher ADC value than non clear cell RCC. Conclusion: DWI-MRI has a role in differentiation of benign and malignant renal masses and the characterization of different malignant categories, subtypes and grades. |
| Databáze: | OpenAIRE |
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