CYTOKINES AND HISTOPATHOLOGIC PATTERN OF MALIGNANT NEOPLASMS IN GASTROINTESTINAL CANCER
| Autor: | M. Yu. Rukavishnikov, Yu. N. Kozlova, Elena Mikhailova, A. I. Autenshluss, Nikolay Varaksin, A. V. Sosnina, A. V. Kan’shina, D. V. Morozov |
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| Rok vydání: | 2014 |
| Předmět: |
gastorintestinal cancer
medicine.medical_treatment Immunology RC581-607 Biology malignant neoplasm medicine.disease cytokines Malignancy grade Cytokine medicine biology.protein antibodies Immunology and Allergy Tumor necrosis factor alpha Gastrointestinal cancer Immunologic diseases. Allergy Antibody histopatologic pattern |
| Zdroj: | Medicinskaâ Immunologiâ, Vol 11, Iss 1, Pp 29-34 (2014) |
| ISSN: | 2313-741X 1563-0625 |
| Popis: | The patients with gastrointestinal cancer exhibit high contents of TNFα, IL-1β, IL-2, IL-6, IL-8, IFNγ, IL-1Ra and increased levels of anti-IFNα antibodies. Significant correlations are detected between histopathological parameters of the tumors, and the levels of TNFα, IL-2, IL-6, IL-8, IFNα, IFNγ, as well as antibodies against TNFα и IFNα. Moreover, we have determined diagnostically significant levels of cytokines and their combinations. On the basis of estimated diagnostic values, one may evaluate both current status of the tumor, as well as its potential malignancy grade. |
| Databáze: | OpenAIRE |
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