Analysis of diterpenoid compounds from the latex of two Euphorbiaceae by liquid chromatography‒electrospray ionisation mass spectrometry
| Autor: | A M Sobottka, C Görick, Matthias F. Melzig |
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| Rok vydání: | 2015 |
| Předmět: |
Electrospray
Spectrometry Mass Electrospray Ionization Latex Plant Science Biology Mass spectrometry 01 natural sciences Biochemistry Phorbol ester Analytical Chemistry chemistry.chemical_compound Organic chemistry Euphorbia papillosa Chromatography 010405 organic chemistry Organic Chemistry Euphorbiaceae biology.organism_classification Sapium glandulosum Terpenoid 0104 chemical sciences 010404 medicinal & biomolecular chemistry chemistry Diterpene Diterpenes Chromatography Liquid |
| DOI: | 10.6084/m9.figshare.1569268 |
| Popis: | The latex of Euphorbia papillosa A.St.-Hil. and Sapium glandulosum (L.) Morong was phytochemically investigated by liquid chromatography/mass spectrometry. The results reveal the presence of tigliane-type diterpenoid compounds, particularly 12-deoxyphorbol esters, in both species. In addition, ingenane-type diterpene esters were found in the latex of E. papillosa. The latex of S. glandulosum showed only tigliane-type diterpenes, confirming the literature data on this genus. According to mass data, we are proposing the presence of 10 compounds derived from 12-deoxyphorbol monoesters and diesters, from one 12-deoxyphorbaldehyde, from two ingenol derivatives and from one nitrogen-containing phorbol ester in the latex of the analysed species. Considering that 12-deoxy tigliane diterpenes are described as antitumour and antiviral agents, these results indicate a pharmacological potential for these two Euphorbiaceae species. |
| Databáze: | OpenAIRE |
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