Cholinesterase in plasma: first reported absence in the Bantu; half-life determination
| Autor: | Doris Balinsky, D. W. Patient, Trefor Jenkins |
|---|---|
| Rok vydání: | 1967 |
| Předmět: |
medicine.medical_specialty
Heterozygote Multidisciplinary biology Adolescent Homozygote Dibucaine Half-life Black People Heterozygote advantage Bantu languages Succinylcholine Fluorides Endocrinology Internal medicine Genes Regulator biology.protein medicine Cholinesterases Humans Female Antibody Metabolism Inborn Errors Cholinesterase |
| Zdroj: | Science (New York, N.Y.). 156(3783) |
| ISSN: | 0036-8075 |
| Popis: | A Bantu schoolgirl is the first non-Caucasoid found homozygous for the "silent" cholinesterase gene. Investigation of her family revealed two heterozygotes. The propositus possesses no antibody to normal cholinesterase. Transfused cholinesterase had in her a half-life of approximately 10 days. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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