Physical activity and inactivity among different body composition phenotypes in individuals with moderate to very severe chronic obstructive pulmonary disease
| Autor: | Larissa G. Sartori, Lorena Paltanin Schneider, Karina Couto Furlanetto, Nidia A. Hernandes, Daniele C. Dala Pola, Mariana P. Bertoche, Carlos Augusto Camillo, Diery Fernandes Rugila, R. P. Hirata, Felipe Vilaça Cavalari Machado, Fabio Pitta |
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| Přispěvatelé: | RS: NUTRIM - R3 - Respiratory & Age-related Health, Pulmonologie |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Spirometry
REHABILITATION medicine.medical_specialty SYSTEMIC INFLAMMATION PROGNOSIS Physical activity Physical Therapy Sports Therapy and Rehabilitation Body composition EXERCISE CAPACITY VALIDATION SARCOPENIA Body Mass Index Pulmonary Disease Chronic Obstructive 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans COPD Orthopedics and Sports Medicine Muscle Strength 030212 general & internal medicine Exercise Aged Original Research Respiratory tract diseases medicine.diagnostic_test business.industry MORTALITY ADULTS Exercise capacity medicine.disease Obesity Phenotype 030228 respiratory system Sarcopenia OBESITY Lungs business Body mass index |
| Zdroj: | Braz J Phys Ther Revista Brasileira de Fisioterapia, 25(3), 296-302. Revista Brasileira de Fisioterapia |
| ISSN: | 1413-3555 |
| DOI: | 10.1016/j.bjpt.2020.07.005 |
| Popis: | Background: The phenotype profiling of individuals with chronic obstructive pulmonary disease (COPD) according to impairments in body composition and level of physical activity in daily life (PADL) needs to be determined.Objective: To verify if individuals with COPD classified as physically active/inactive present different characteristics within different body composition phenotypes.Methods: Individuals with COPD were cross-sectionally stratified into four groups according to fat-free and fat mass indexes: Normal Body Composition (NBC), Obese (Ob), Sarcopenic (Sarc), and Sarcopenic/Obese (Sarc/Ob). Additionally, individuals had their PADL level objectively assessed through activity monitoring during two weekdays for at least 10 h/day, and then were classified as physically active (Act) or inactive (Inact) according to international recommendations. Lung function (spirometry), exercise capacity (6-minute walking test [6MWT]) and peripheral muscle strength (1-repetition maximum [1RM]) were also assessed. 176 individuals with COPD (mean +/- standard deviation age: 67 +/- 8 years, body mass index 26 +/- 6 kg/m(2), FEV1 47 +/- 16%predicted) were classified as: NBC + Act (17%), NBC + Inact( 22%), Ob + Act (6%), Ob + Inact (10%), Sarc + Act (12%), Sarc + Inact (9%), Sarc/Ob + Act (8%) and Sarc/ Ob + Inact (16%). The Sarc/Ob + Inact group presented lower 6MWT and 1RM for knee extension compared to NBC + Act, NBC + Inact, and Ob + Act groups (p < 0.05). The Sarc/Ob + Inactgroup also presented lower FEV1% predicted, 1RM for elbow flexion and elbow extension compared to the NBC + Act and NBC + Inact groups and lower 1RM for elbow extension compared to Ob + Inact group (p < 0.05).Conclusion: The combination of sarcopenia, obesity, and physical inactivity was shown to be detrimental in individuals with COPD. Therefore, this profile is a main therapeutic target for improving PADL level and/or body composition. (C) 2020 Associacao Brasileira de Pesquisa e Pos-Graduacao em Fisioterapia. Published by Elsevier Editora Ltda. All rights reserved. |
| Databáze: | OpenAIRE |
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