Long-Range C–H Bond Activation by RhIII-Carboxylates

Autor:	Robert J. Nielsen, Michal Sabat, Ross Fu, T. Brent Gunnoe, William A. Goddard, Matthew E. O'Reilly
Rok vydání:	2014
Předmět:	chemistry.chemical_classification Range (particle radiation) C h bond Base (chemistry) Chemistry Xylene Inorganic chemistry General Chemistry Biochemistry Medicinal chemistry Catalysis Ion chemistry.chemical_compound Colloid and Surface Chemistry Deprotonation Pyridine
Zdroj:	Journal of the American Chemical Society. 136:14690-14693
ISSN:	1520-5126 0002-7863
DOI:	10.1021/ja508367m
Popis:	Traditional C–H bond activation by a concerted metalation–deprotonation (CMD) mechanism involves precoordination of the C–H bond followed by deprotonation from an internal base. Reported herein is a “through-arene” activation of an uncoordinated benzylic C–H bond that is 6 bonds away from a Rh^(III) ion. The mechanism, which was investigated by experimental and DFT studies, proceeds through a dearomatized xylene intermediate. This intermediate was observed spectroscopically upon addition of a pyridine base to provide a thermodynamic trap.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39fba58b5ae433419695703e2f5ae07b https://doi.org/10.1021/ja508367m Zobrazit plný text záznamu