Postmenopausal hyperandrogenism of ovarian origin: A clinicopathologic study of five cases

Autor: EK Omana, George Beena, S Ajith, Nitu Mariam Mathew
Rok vydání: 2016
Předmět:
Zdroj: Journal of Mid-Life Health, Vol 7, Iss 4, Pp 189-192 (2016)
Journal of Mid-Life Health
ISSN: 0976-7800
DOI: 10.4103/0976-7800.195699
Popis: In postmenopausal women presenting with virilization and elevated testosterone levels, laparoscopic salpingo-oophorectomy should be considered after exclusion of adrenal causes. A clinicopathological study was conducted among those women who presented with features of hyperandrogenism in our postmenopausal clinic over a period of 2 years. Relevant past medical and surgical histories were elicited. Basic hormonal evaluation and radiological imaging were done. Laparoscopic bilateral salpingo-oophorectomy was done. Six weeks postoperatively, serum testosterone was undetectable with significant clinical improvement. There was no recurrence of symptoms during the follow-up period of 2 years. Treatment of postmenopausal women with hyperandrogenism and virilization with laparoscopic bilateral salpingo-oophorectomy is effective if she has no pronounced ovarian enlargement or adrenal tumor on imaging. An extensive endocrine testing and a detailed search for metastatic disease may be unnecessary.
Databáze: OpenAIRE