Non-lupus full-house nephropathy: a case series
Autor: | Márcia de Oliveira Silva, Gyl Eanes Barros Silva, Joyce Santos Lages, Pedro Henrique Cavalcante Vale, Rinadja de Melo Cunha, Ricardo Ferreira Santos, Felipe Leite Guedes, Patrick Vanttinny Vieira de Oliveira, Dyego José de Araújo Brito, Natalino Salgado Filho |
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Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
030232 urology & nephrology Lupus nephritis Immunofluorescence Nephropathy 03 medical and health sciences 0302 clinical medicine immune system diseases medicine Kidney injury Lupus Erythematosus Systemic skin and connective tissue diseases 030203 arthritis & rheumatology Systemic lupus erythematosus medicine.diagnostic_test business.industry General Medicine medicine.disease Lupus Nephritis Dermatology Diseases of the genitourinary system. Urology Fluorescent Antibody Technique Autoimmune inflammatory disease RC870-923 Histological pattern business |
Zdroj: | Brazilian Journal of Nephrology, Vol 43, Iss 4, Pp 586-590 (2020) |
ISSN: | 2175-8239 0101-2800 |
DOI: | 10.1590/2175-8239-jbn-2019-0242 |
Popis: | Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune inflammatory disease. However, some patients may exhibit a histological pattern of kidney injury, with characteristics indistinguishable from lupus nephritis, but without presenting any extrarenal symptoms or serologies suggestive of SLE. Such involvement has recently been called non-lupus full-house nephropathy. The objective is to report a series of clinical cases referred to the Laboratory of the Federal University of Maranhão that received the diagnosis of "full-house" nephropathy unrelated to lupus, upon immunofluorescence and to discuss its evolution and outcomes. Non-lupus full-house nephropathy represents a diagnostic and therapeutic challenge, because it is a new entity, which still needs further studies and may be the initial manifestation of SLE, isolated manifestation of SLE or a new pathology unrelated to SLE. |
Databáze: | OpenAIRE |
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