Individual variation in 3-methylbutanal: a putative link between human leukocyte antigen and skin microflora
| Autor: | L. Morris Gosling, S. Craig Roberts, Sanjay Antony-Babu, Anthony G. O'Donnell, Huitu Wang, Sergey U. Savelev, Marion Petrie, Alan C. Ward, Michael Goodfellow, Anthony S. Clare |
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| Rok vydání: | 2006 |
| Předmět: |
chemistry.chemical_classification
Adult Male Aldehydes Analysis of Variance Sensory system Peptide General Medicine Human leukocyte antigen Biology Biochemistry In vitro Mating preferences Gas Chromatography-Mass Spectrometry Odor chemistry HLA Antigens Odorants Humans Female Gas chromatography–mass spectrometry Gene Ecology Evolution Behavior and Systematics Skin |
| Zdroj: | Journal of chemical ecology. 34(9) |
| ISSN: | 0098-0331 |
| Popis: | The human derma emits volatile compounds whose interaction with a receiver's olfactory sensory system may affect individual recognition and mating preferences. Studies suggest that both genes and environmental factors determine characteristic odor of an individual. We used solid-phase microextraction and gas chromatography-mass spectrometry to identify 3-methylbutanal in human axillary odor; we showed that the abundance of this volatile compound varies significantly among individuals and demonstrated that its formation in vitro may be influenced by interaction between human leukocyte antigen peptide and dermal microflora. |
| Databáze: | OpenAIRE |
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