Neoepitopes as Difference Makers for General Cancer Vaccines?
| Autor: | Walter J. Storkus, Jessica N. Filderman |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Oncology Cancer Research medicine.medical_specialty business.industry medicine.medical_treatment Cancer Immunotherapy medicine.disease Cancer Vaccines 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Antigens Neoplasm 030220 oncology & carcinogenesis Internal medicine Neoplasms Mutation medicine Humans business Disease prognosis |
| Zdroj: | Clinical cancer research : an official journal of the American Association for Cancer Research. 26(17) |
| ISSN: | 1557-3265 |
| Popis: | The cancer mutanome has been associated with disease prognosis as well as response to interventional immunotherapy and provides a substrate for development of personalized vaccines targeting tumor neoepitopes. Recent findings suggest that neoantigen-based vaccines may represent general interventional approaches for patients with solid cancers, regardless of their inherent mutational burden.See related article by Fang et al., p. 4511 |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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