Small-molecule efflux pump inhibitors from natural products as a potential source of antimicrobial agents

Autor:	Shiv Gupta, Sanjay M. Jachak, Pallavi Ahirrao, Somendu Kumar Roy, Simon Gibbons
Rok vydání:	2012
Předmět:	chemistry.chemical_compound Chemistry Polyphenol Curcumin food and beverages Potential source Efflux Drug resistance Antimicrobial Combinatorial chemistry Small molecule
Zdroj:	Scopus-Elsevier
Popis:	This chapter discusses the potential use of natural products as efflux pump inhibitors (EPIs) in several drug-resistant microbial pathogens, i.e., Mycobacterium, Staphylococcus aureus, Candida albicans. These natural products include various plant flavonoids, curcumin, polyphenols, diterpenes, oligosaccharides and alkaloids. In vitro assays used to screen EPI-related activities of these natural compounds are also outlined.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39e3bd11c59d0c0352df151ddddc3962 https://doi.org/10.1079/9781845939434.0062 Zobrazit plný text záznamu