Liver Transplant Patients with High Preoperative Serum Bilirubin Levels Are at Increased Risk of Postoperative Delirium: A Retrospective Study
| Autor: | Hyo Jung Son, Yoon Sook Lee, Gene Hyun Park, Yoon Ji Choi, Jae Ryong Shim, Hyun-Su Ri, Kyu Hee Park, Ju Yeon Park |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Bilirubin
medicine.medical_treatment lcsh:Medicine complication Liver transplantation behavioral disciplines and activities Article postoperative delirium 03 medical and health sciences Liver disease chemistry.chemical_compound 0302 clinical medicine mental disorders medicine Risk factor liver transplantation business.industry Medical record lcsh:R Retrospective cohort study General Medicine medicine.disease nervous system diseases chemistry 030220 oncology & carcinogenesis Anesthesia Delirium 030211 gastroenterology & hepatology medicine.symptom bilirubin Complication business |
| Zdroj: | Journal of Clinical Medicine Volume 9 Issue 5 Journal of Clinical Medicine, Vol 9, Iss 1591, p 1591 (2020) |
| ISSN: | 2077-0383 |
| DOI: | 10.3390/jcm9051591 |
| Popis: | Postoperative delirium is a common complication after liver transplantation (LT). A high model for end-stage liver disease (MELD) score is an independent risk factor for postoperative delirium, but it is unclear which of the components of this score are risk indicators. The aim of this study was to analyze the incidence of postoperative delirium according to the preoperative serum bilirubin level, a component of the MELD score, in patients who underwent LT. The medical records of 325 patients who underwent LT from January 2010 to February 2019 at a single university hospital were retrospectively reviewed. The patients were divided into two groups: those who experienced postoperative delirium (Delirium group, n = 69) and those who did not (Control group, n = 256). Data on the patients&rsquo demographic characteristics, perioperative management, and postoperative complications were collected. Mean preoperative bilirubin level was higher in the Delirium group than in the Control group (p < 0.0001). In the Delirium group, 54 (78.26%) patients had preoperative bilirubin levels above 3.5 mg/dL. In the multivariate analysis, preoperative bilirubin above 3.5 mg/dL was associated with postoperative delirium (p = 0.002). Therefore, preoperative hyperbilirubinemia is an independent risk factor for postoperative delirium. |
| Databáze: | OpenAIRE |
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