LIFESTAT – Living with statins: An interdisciplinary project on the use of statins as a cholesterol-lowering treatment and for cardiovascular risk reduction
| Autor: | Steen Larsen, Anja Birk Kuhlman, John Sahl Andersen, Maria Nathalie Angleys Olsen, Ian D. Hickson, Bjarke Oxlund, A. Heltberg, Sofie Rosenlund Lau, Thomas Morville, Kasper Bering Liisberg, Birgitte Bruun, Margit Kriegbaum, Tine Lovsø Dohlmann, Christa Lykke Christensen, Flemming Dela, Jørn Wulff Helge, Allan Krasnik, Lene Juel Rasmussen |
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| Rok vydání: | 2016 |
| Předmět: |
Gerontology
Health Knowledge Attitudes Practice medicine.medical_specialty Denmark General Practice Information Seeking Behavior Population Alternative medicine Disease 030204 cardiovascular system & hematology Risk Assessment Cohort Studies 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Epidemiology Humans Medicine Mass Media 030212 general & internal medicine education education.field_of_study business.industry Cholesterol Mechanism (biology) Anticholesteremic Agents Public Health Environmental and Occupational Health General Medicine Treatment Outcome chemistry Cardiovascular Diseases Physical therapy Hydroxymethylglutaryl-CoA Reductase Inhibitors business Risk assessment Cohort study |
| Zdroj: | Christensen, C L, Helge, J W, Krasnik, A, Kriegbaum, M, Rasmussen, L J, Hickson, I D, Liisberg, K B, Oxlund, B, Bruun, B, Lau, S R, Olsen, M N A, Andersen, J S, Heltberg, A S, Kuhlman, A C B, Morville, T H, Dohlmann, T L, Larsen, S & Dela, F 2016, ' LIFESTAT – Living with statins : An interdisciplinary project on the use of statins as a cholesterol-lowering treatment and for cardiovascular risk reduction ', Scandinavian Journal of Public Health, vol. 44, no. 5, pp. 534-539 . https://doi.org/10.1177/1403494816636304 |
| ISSN: | 1651-1905 1403-4948 |
| DOI: | 10.1177/1403494816636304 |
| Popis: | AIM:LIFESTAT is an interdisciplinary project that leverages approaches and knowledge from medicine, the humanities and the social sciences to analyze the impact of statin use on health, lifestyle and well-being in cohorts of Danish citizens. The impetus for the study is the fact that 10% of the population in the Scandinavian countries are treated with statins in order to maintain good health and to avoid cardiovascular disease by counteracting high blood levels of cholesterol. The potential benefit of treatment with statins should be considered in light of evidence that statin use has prevalent and unintended side effects (e.g. myalgia, and glucose and exercise intolerance).METHODS:The LIFESTAT project combines invasive human experiments, biomedical analyses, nationwide surveys, epidemiological studies, qualitative interviews, media content analyses, and ethnographic participant observations. The study investigates the biological consequences of statin treatment; determines the mechanism(s) by which statin use causes muscle and mitochondrial dysfunction; and analyzes achievement of treatment goals, people's perception of disease risk, media influence on people's risk and health perception, and the way people manage to live with the risk (personally, socially and technologically). CONCLUSIONS THE ORIGINALITY AND SUCCESS OF LIFESTAT DEPEND ON AND DERIVE FROM ITS INTERDISCIPLINARY APPROACH, IN WHICH THE DISCIPLINES CONVERGE INTO THOROUGH AND HOLISTIC STUDY AND DESCRIBE THE IMPACT OF STATIN USE ON THE EVERYDAY LIFE OF STATIN USERS THIS HAS THE POTENTIAL FOR MUCH GREATER BENEFIT THAN ANY ONE OF THE DISCIPLINES ALONE INTEGRATING TRADITIONAL DISCIPLINES PROVIDES NOVEL PERSPECTIVES ON POTENTIAL CURRENT AND FUTURE SOCIAL, MEDICAL AND PERSONAL BENEFITS OF STATIN USE. |
| Databáze: | OpenAIRE |
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