Orthotopic Neobladder Versus Indiana Pouch in Women: A Comparison of Health Related Quality of Life Outcomes
| Autor: | Scott E. Eggener, Mark H. Katz, Sergey Shikanov, Gary D. Steinberg, Michael C. Large |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
medicine.medical_specialty
Urology Urinary system medicine.medical_treatment Urinary Diversion Cystectomy Quality of life medicine Humans Aged Retrospective Studies Urinary bladder business.industry Urinary Reservoirs Continent Urinary diversion Retrospective cohort study Middle Aged Surgery stomatognathic diseases Treatment Outcome medicine.anatomical_structure Quality of Life Indiana pouch Female business Continent Urinary Diversion |
| Zdroj: | Journal of Urology. 183:201-206 |
| ISSN: | 1527-3792 0022-5347 |
| DOI: | 10.1016/j.juro.2009.08.148 |
| Popis: | Little is known about the health related quality of life of women who have undergone continent urinary diversion. We compared health related quality of life outcomes for women who underwent radical cystectomy with an orthotopic neobladder or Indiana pouch.From 1995 to June 2008 a single surgeon (GDS) performed radical cystectomy with an orthotopic neobladder in 47 women and radical cystectomy with an Indiana pouch in 45. A comprehensive database provided clinical, pathological and outcomes data. The validated Functional Assessment of Cancer Therapy-Vanderbilt Cystectomy Index was mailed to 92 patients.Complete data were available for 87% of patients treated with radical cystectomy with an orthotopic neobladder and 93% of those treated with radical cystectomy with an Indiana pouch, with a median followup of 34 and 24 months, respectively (p = 0.8). Median (IQR) age was 65 (58, 71) and 61.5 (51, 67) years for patients with an orthotopic neobladder and Indiana pouch, respectively (p = 0.03). No significant differences were found for pathological stage, nodal status, blood loss, Clavien grade III or greater complications, adjuvant therapy or hospital stay between the 2 treatment groups, or between respondents and nonrespondents. Five-year survival rates for patients with an orthotopic neobladder and Indiana pouch were 65% and 58%, respectively (p = 0.9). There were 21 (75%) living patients with an orthotopic neobladder and 19 (61%) with an Indiana pouch who completed the Functional Assessment of Cancer Therapy-Vanderbilt Cystectomy Index, and physical (p = 0.53), social (p = 0.97), emotional (p = 0.61), functional (p = 0.55) and radical cystectomy specific (p = 0.54) health related quality of life domains were not significantly different between the groups.Women undergoing radical cystectomy with an orthotopic neobladder vs an Indiana pouch have similar health related quality of life outcomes. Larger series with longer followup and multiple surgeons are necessary to confirm these findings. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|