Usefulness of iodine-blood material density images in estimating degree of liver fibrosis by calculating extracellular volume fraction obtained from routine dual-energy liver CT protocol equilibrium phase data: preliminary experience
| Autor: | Ryotaro Yamamoto, Keiko Sakamoto, Keisuke Sato, Emi Ito, Hiroshi Urakawa, Kengo Yoshimitsu |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Liver Cirrhosis Male chemistry.chemical_element Contrast Media Vena Cava Inferior Iodine Chronic liver disease Inferior vena cava 030218 nuclear medicine & medical imaging 03 medical and health sciences Equilibrium phase 0302 clinical medicine Fibrosis medicine.artery Medicine Humans Radiology Nuclear Medicine and imaging Aorta Abdominal Aged Retrospective Studies Aged 80 and over Extracellular volume fraction medicine.diagnostic_test business.industry Diagnostic Tests Routine Abdominal aorta Middle Aged medicine.disease medicine.vein chemistry 030220 oncology & carcinogenesis cardiovascular system Elasticity Imaging Techniques Female Elastography business Nuclear medicine Tomography X-Ray Computed Algorithms |
| Zdroj: | Japanese journal of radiology. 38(4) |
| ISSN: | 1867-108X |
| Popis: | To assess whether extracellular volume fraction (ECV) calculated from iodine(-blood) density images (I-B) of dual-energy liver CT (DECT) equilibrium phase data (EqD) is useful in estimating the degree of liver fibrosis. Consecutive 52 patients with chronic liver disease who underwent fast kV switching DECT and liver MR elastography (MRE) were retrospectively enrolled. Iodine(-water) density images (I-W) and I-B generated from EqD and ECV were calculated. As blood pools, abdominal aorta (Ao) and suprahepatic inferior vena cava (IVC) were chosen, and, therefore, 4 types of ECV (ECVI-W Ao, ECVI-W IVC, ECVI-B Ao, ECVI-B IVC) were obtained. ECV was also calculated using conventional method (ECVconv Ao). The correlation coefficients (R2 or rho) of these five ECVs versus liver stiffness (MRE) or pathologically proven fibrosis grades were compared. As for correlation with liver stiffness, R2 for ECVconv.Ao, ECVI-W Ao, ECVI-B Ao, ECVI-W IVC, and ECVI-B IVC, were 0.26, 0.34, 0.44, 0.39, and 0.52, respectively (all p |
| Databáze: | OpenAIRE |
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