Préservation de la fertilité en cancérologie
| Autor: | Vorilhon S, Hanae Pons, Anne-Sophie Gremeau, Cécile Moluçon Chabrot, Jean-Luc Pouly, Victoria Grèze, Laure Chaput, Florence Brugnon |
|---|---|
| Přispěvatelé: | CHU Estaing [Clermont-Ferrand], CHU Clermont-Ferrand, Laboratoire BDR CECOS - FIV AMP, CHU Clermont-Ferrand-CHU Clermont-Ferrand, Imagerie Moléculaire et Stratégies Théranostiques (IMoST), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020]), Service d’Hématologie Biologique [CHU Clermont-Ferrand], CHU Gabriel Montpied [Clermont-Ferrand], CHU Clermont-Ferrand-CHU Clermont-Ferrand-CHU Estaing [Clermont-Ferrand] |
| Jazyk: | francouzština |
| Rok vydání: | 2018 |
| Předmět: |
Cancer Research
media_common.quotation_subject [SDV]Life Sciences [q-bio] Physiology Context (language use) Fertility Ovary [SDV.BC]Life Sciences [q-bio]/Cellular Biology [SDV.MHEP.GEO]Life Sciences [q-bio]/Human health and pathology/Gynecology and obstetrics Cryopreservation 03 medical and health sciences 0302 clinical medicine medicine Radiology Nuclear Medicine and imaging Fertility preservation [SDV.BDD]Life Sciences [q-bio]/Development Biology ComputingMilieux_MISCELLANEOUS media_common 030219 obstetrics & reproductive medicine business.industry [SDV.BA]Life Sciences [q-bio]/Animal biology Cancer [SDV.BDLR]Life Sciences [q-bio]/Reproductive Biology Hematology General Medicine [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism medicine.disease Sperm 3. Good health In vitro maturation medicine.anatomical_structure Oncology 030220 oncology & carcinogenesis business |
| Zdroj: | Bulletin du Cancer Bulletin du Cancer, John Libbey Eurotext, 2018, 105 (1), pp.99-110. ⟨10.1016/j.bulcan.2017.11.001⟩ Bulletin du Cancer, 2018, 105 (1), pp.99-110. ⟨10.1016/j.bulcan.2017.11.001⟩ |
| ISSN: | 0007-4551 1769-6917 |
| DOI: | 10.1016/j.bulcan.2017.11.001⟩ |
| Popis: | Since the improvement of cancer diagnosis and treatment, survival rates of these patients increase. Gonadal damages are frequent consequences of cancer treatments with different evidence of impaired fertility. In this context, fertility preservation should be proposed to patients exposed to potentially gonadotoxic treatments. Different preservation approaches may be proposed depending on patient age, sex, cancer type and type of treatment. The indications of fertility preservation depend on sexual maturity. In young girls, ovarian cortex cryopreservation is the only technique feasible in order to preserve their reproductive potential. Vitrification of oocytes which needs ovarian stimulation or oocytes in vitro maturation is becoming more commonly performed for pubertal women to preserve their fertility. Ovarian cortex freezing could be offered to emergency fertility preservation of adult female cancer patients. In prepubertal boys, testicular tissue cryopreservation is the only line treatment for fertility preservation. For future use, various approaches are being evaluated such as spermatogonial stem cell injection or in vitro maturation. Cryopreservation of spermatozoa is, today, an established and successful technique for male adults. When there are no spermatozoa in ejaculate, sperm can be retrieved after treatment of testicular biopsy. The French bioethics law clearly indicates that fertility preservation should be proposed to patients exposed to potentially gonadotoxic treatment. Today, many approaches are possible. Fertility preservation indications are based on multidisciplinary consultations within platforms for the fertility preservation in order to optimize the patient care. |
| Databáze: | OpenAIRE |
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