The impact of COVID‐19 lockdown on brain metabolism
| Autor: | Jacques-Yves Campion, Eric Guedj, Tatiana Horowitz, Mathieu Ceccaldi, Fanny Barthelemy, Serge Cammilleri |
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| Přispěvatelé: | Institut FRESNEL (FRESNEL), Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Centre National de la Recherche Scientifique (CNRS), Hôpital de la Timone [CHU - APHM] (TIMONE), Centre Européen de Recherche en Imagerie médicale (CERIMED), Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)-École Centrale de Marseille (ECM)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Centre National de la Recherche Scientifique (CNRS), Imagerie MOléculaire pour applications THéranostiques personnalisées (IMOTHEP), Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Centre National de la Recherche Scientifique (CNRS)- Hôpital de la Timone [CHU - APHM] (TIMONE), Institut de Neurosciences des Systèmes (INS), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Otten, Lisa |
| Rok vydání: | 2021 |
| Předmět: |
Male
deconditioning Emotions Physiology SARS‐CoV‐2 lockdown Deconditioning Cortex (anatomy) Longitudinal Studies Social isolation FDG-PET long COVID Research Articles Aged 80 and over Radiological and Ultrasound Technology Motor Cortex Brain Cognition Middle Aged medicine.anatomical_structure Social Isolation Neurology Quarantine Female Anatomy medicine.symptom Research Article deconfinement FDG‐PET Coronavirus disease 2019 (COVID-19) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Context (language use) pyramidal tract Post-Acute COVID-19 Syndrome COVID‐19 Fluorodeoxyglucose F18 medicine Humans Radiology Nuclear Medicine and imaging Exercise Pandemics Aged Retrospective Studies Pyramidal tracts SARS-CoV-2 business.industry [SCCO.NEUR]Cognitive science/Neuroscience [SCCO.NEUR] Cognitive science/Neuroscience physical activities COVID-19 Somatosensory Cortex brain metabolism Positron-Emission Tomography Neurology (clinical) Nerve Net Radiopharmaceuticals business |
| Zdroj: | Human Brain Mapping Human Brain Mapping, 2021, 43 (2), pp.593-597. ⟨10.1002/hbm.25673⟩ |
| ISSN: | 1097-0193 1065-9471 |
| Popis: | This study aims to evaluate the impact of French national lockdown of 55 days on brain metabolism of patients with neurological disorders. Whole‐brain voxel‐based PET analysis was used to correlate 18F‐FDG metabolism to the number of days after March 17, 2020 (in 95 patients; mean age: 54.3 years ± 15.7; 59 men), in comparison to the same period in 2019 before the SARS‐CoV‐2 outbreak (in 212 patients; mean age: 59.5 years ± 15.8; 114 men), and to the first 55 days of deconfinement (in 188 patients; mean age: 57.5 years ± 16.5; 93 men). Lockdown duration was negatively correlated to the metabolism of the sensory‐motor cortex with a prevailing effect on the left dominant pyramidal tract and on younger patients, also including the left amygdala, with only partial reversibility after 55 days of deconfinement. Weak overlap was found with the reported pattern of hypometabolism in long COVID ( Lockdown duration is negatively correlated to the metabolism of the sensory‐motor cortex with a prevailing effect on the left dominant pyramidal tract and on younger patients, also including the left amygdala, with only partial reversibility after 55 days of deconfinement. Weak overlap is found with the reported pattern of hypometabolism in long COVID ( |
| Databáze: | OpenAIRE |
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