Epidural anesthesia and analgesia in high-risk surgical patients
| Autor: | Mark P. Yeager, Truls Brinck-Johnsen, Raymond K. Neff, D. David Glass |
|---|---|
| Rok vydání: | 1987 |
| Předmět: |
Anesthesia
Epidural Risk medicine.medical_specialty Urinary system Analgesic Random Allocation medicine Humans Local anesthesia Risk factor Aged Clinical Trials as Topic Pain Postoperative business.industry Postoperative complication Prognosis Surgery Clinical trial Anesthesiology and Pain Medicine Anesthesia Anesthetic Costs and Cost Analysis Analgesia Complication business medicine.drug |
| Zdroj: | Anesthesiology. 66(6) |
| ISSN: | 0003-3022 |
| Popis: | The authors conducted a randomized controlled clinical trial to evaluate the effect of epidural anesthesia and postoperative analgesia (EAA) on postoperative morbidity in a group of high-risk surgical patients. A total of 53 patients were admitted to the study, 28 received EAA, and 25 received standard anesthetic and analgesic techniques without EAA. Surgical "risk" was evaluated preoperatively and found to be comparable in the two groups. When compared to control patients, patients who received EAA had a reduction in the overall postoperative complication rate (P = 0.002) and in the incidence of cardiovascular failure (P = 0.007) and major infectious complications (P = 0.007). Urinary cortisol excretion, a marker of the stress response, was significantly diminished during the first 24 postoperative hours in the group receiving EAA (P = 0.025). Finally, hospital costs were significantly reduced for patients who received EAA (P = 0.02). The authors conclude that EAA exerted a significant beneficial effect on operative outcome in a group of high risk surgical patients. |
| Databáze: | OpenAIRE |
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