Quantitative analysis of tribromsalan in blood and urine

Autor:	R.J. Steltenkamp, H.S. Chun Hong, N.L. Smith
Rok vydání:	1975
Předmět:	Chromatography medicine.diagnostic_test Silica gel Extraction (chemistry) Ethyl acetate Pharmaceutical Science Urine Hydrogen-Ion Concentration TRIBROMSALAN Salicylanilides chemistry.chemical_compound Spectrometry Fluorescence chemistry Spectrophotometry Salicylamides medicine Methods Animals Humans Chromatography Thin Layer Rabbits Quantitative analysis (chemistry) Whole blood Disinfectants
Zdroj:	Journal of pharmaceutical sciences. 64(12)
ISSN:	0022-3549
Popis:	Tribromsalan can be quantitatively measured in whole blood and urine by a technique involving extraction with ethyl acetate, treatment with silica gel, separation by TLC, and quantitative measurement by fluorescent spectrophotometry. This method has a sensitivity down to 125 ng (25 ppb in 5.0 ml of sample) of free tribromsalan and shows an average 90% recovery of tribromsalan in blood and urine with standard deviations of 9.7 and 7.4%, respectively.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39b65dee19d1a250733078027aa2e010 https://pubmed.ncbi.nlm.nih.gov/1513 Zobrazit plný text záznamu Plný text