A 90-kDa surface antigen of immature smooth muscle cells is ICAM-1
| Autor: | A. V. Tjurmin, O. Yu. Printseva, A. M. Gown, M. M. Peclo |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Pulmonary and Respiratory Medicine
Radioimmunoprecipitation Assay Pathology medicine.medical_specialty Endothelium Arteriosclerosis medicine.drug_class Physiology Biology Monoclonal antibody Muscle Smooth Vascular Fetus Antigen Physiology (medical) medicine Humans Aorta ICAM-1 CD40 Staining and Labeling Mesenchymal stem cell Antibodies Monoclonal Cell Biology Intercellular Adhesion Molecule-1 Immunohistochemistry Molecular biology Molecular Weight medicine.anatomical_structure Cell culture Antigens Surface biology.protein Antibody Cardiology and Cardiovascular Medicine Cell Adhesion Molecules |
| Zdroj: | American Journal of Physiology-Lung Cellular and Molecular Physiology. 261:L21-L22 |
| ISSN: | 1522-1504 1040-0605 |
| DOI: | 10.1152/ajplung.1991.261.4.l21 |
| Popis: | A monoclonal antibody, designated 10F3, that reacts with an antigen of molecular mass 90,000 Da has been developed by immunization of BALB/c mice with smooth muscle cells in long-term culture. The cells were originally isolated from fetal human aorta. The 10F3 was identified as an antibody that reacts with the ICAM-1 molecule. ICAM-1 is a mesenchymal antigen that is lost during differentiation of cells other than endothelium but is reexpressed by the intimal cells of vessels involved in atherogenesis. atherosclerosis; monoclonal antibodies |
| Databáze: | OpenAIRE |
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