Clinical Features, Risk Factors, and Treatment Experience: A Review of 74 Patients with ST-segment Elevation Myocardial Infarction Complicated by Ventricular Fibrillation
| Autor: | Wei Wang, Yan Bi Wu, Ji Jin Zhu, Quan Fang Chen, Rui Xing Yin, Qi Bin Li, Edward A. Michelson, Hai Hua Chang |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Defibrillation medicine.medical_treatment Myocardial Infarction Risk Factors Internal medicine Humans Medicine ST segment Thrombolytic Therapy cardiovascular diseases Myocardial infarction Cardiopulmonary resuscitation Aged business.industry Mortality rate Thrombolysis Middle Aged medicine.disease Cardiopulmonary Resuscitation Blood pressure Case-Control Studies Ventricular Fibrillation Ventricular fibrillation Emergency Medicine Cardiology Regression Analysis Female business |
| Zdroj: | The Journal of Emergency Medicine. 47:729-735 |
| ISSN: | 0736-4679 |
| DOI: | 10.1016/j.jemermed.2014.06.041 |
| Popis: | Ventricular fibrillation (VF) is one of the most serious complications of acute myocardial infarction, with a high mortality rate. There is a lack of value of rescue thrombolysis in ST-segment elevation myocardial infarction (STEMI) complicated by VF.To examine the relationship between risk factors and mortality, and assess the value of rescue thrombolysis in STEMI complicated by VF.A total 74 cases of STEMI complicated by VF were enrolled. The experimental group consisted of 26 patients who underwent rescue thrombolysis, and the control group included 48 cases without rescue thrombolysis. The two groups were compared in terms of demographic and clinical features including gender, age, onset time, blood pressure, patient's history, creatine kinase-MB, infarct area, complications, therapy, and outcomes, including mortality.The mortality rate of the experimental group was 15.38%, lower than 37.50% of the control group (p0.05). The bleeding rate was 34.62% (n = 9) in the experimental group. The risk factors of smoking, shock, and rescue thrombolysis were correlated with mortality of STEMI complicated by VF (p0.05 for all): Smoking and shock both were positively correlated with mortality, their regression coefficients/odds ratios (OR) were, respectively, 4606/100,041 and 5552/247,711; the rescue thrombolysis was negatively correlated with mortality, its regression coefficient/OR was -1942/0.143.Rescue thrombolysis combined with cardiopulmonary resuscitation and defibrillation is beneficial to patients with STEMI complicated by VF. Smoking, shock upon admission, and lack of rescue thrombolysis were risk factors for mortality in STEMI complicated by VF. |
| Databáze: | OpenAIRE |
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