Analysis of the Saccharomyces cerevisiae proteome with PeptideAtlas
Autor: | King, Nichole L., Deutsch, Eric W., Ranish, Jeffrey A., Nesvizhskii, Alexey I., Eddes, James S., Mallick, Parag, Eng, Jimmy, Desiere, Frank, Flory, Mark, Martin, Daniel B., Kim, Bong, Lee, Hookeun, Raught, Brian, Aebersold, Rudolf |
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Jazyk: | angličtina |
Rok vydání: | 2006 |
Předmět: |
Saccharomyces cerevisiae Proteins
Proteome Genes Fungal Mass spectrometry base proteomics Additional data file Saccharomyces genome database Method Saccharomyces cerevisiae Distribute annotation system respiratory system Life sciences Distinct peptide Mass Spectrometry Molecular Weight Open Reading Frames User-Computer Interface ddc:570 Codon Databases Protein Peptides human activities Hydrophobic and Hydrophilic Interactions |
Zdroj: | Genome Biology Genome Biology, 7 (11) |
ISSN: | 1465-6914 1465-6906 1474-760X |
Popis: | We present the Saccharomyces cerevisiae PeptideAtlas composed from 47 diverse experiments and 4.9 million tandem mass spectra. The observed peptides align to 61% of Saccharomyces Genome Database (SGD) open reading frames (ORFs), 49% of the uncharacterized SGD ORFs, 54% of S. cerevisiae ORFs with a Gene Ontology annotation of 'molecular function unknown', and 76% of ORFs with Gene names. We highlight the use of this resource for data mining, construction of high quality lists for targeted proteomics, validation of proteins, and software development. Genome Biology, 7 (11) ISSN:1474-760X |
Databáze: | OpenAIRE |
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