Molecular aspects of osteoclast function
Autor: | T. J. Hall, T. J. Chambers |
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Rok vydání: | 1996 |
Předmět: |
musculoskeletal diseases
Integrins medicine.medical_specialty Sialoglycoproteins Immunology Pharmacology toxicology Osteoclasts Biology Nitric Oxide Bone resorption Osteoclast Internal medicine medicine Animals Humans Bone Resorption Adenosine Triphosphatases Pharmacology Cathepsins Endocrinology medicine.anatomical_structure Molecular mechanism Osteopontin Reactive Oxygen Species Neuroscience Function (biology) |
Zdroj: | Inflammation Research. 45:1-9 |
ISSN: | 1420-908X 1023-3830 |
DOI: | 10.1007/bf02263497 |
Popis: | In this article we have overviewed recent important advances in understanding the molecular mechanisms involved in osteoclastic bone resorption. Specifically, new findings relating to osteoclast activation and the process of bone resorption are reviewed and a current overall model of how osteoclasts resorb bone is presented. Controversial research topics concerning the regulation of osteoclast activity are also critically discussed. |
Databáze: | OpenAIRE |
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