Secular trends in incidence of type 1 and type 2 diabetes in Hong Kong: A retrospective cohort study
| Autor: | Hongjiang Wu, Juliana C.N. Chan, Andrea O.Y. Luk, Wing-Yee So, Elaine Chow, Alice P.S. Kong, William B. Goggins, Ronald Cw Ma, Eric S.H. Lau, Calvin Ke |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Type 2 diabetes 030204 cardiovascular system & hematology Biochemistry Geographical locations Cohort Studies Endocrinology 0302 clinical medicine Animal Cells Epidemiology Medicine and Health Sciences Diabetes diagnosis and management 030212 general & internal medicine Child Aged 80 and over education.field_of_study Incidence Incidence (epidemiology) General Medicine Middle Aged Type 2 Diabetes Gestational diabetes Child Preschool Medicine Hong Kong Regression Analysis Female Cellular Types Research Article Cohort study Adult medicine.medical_specialty Asia HbA1c Adolescent Endocrine Disorders Immune Cells Immunology Population Antigen-Presenting Cells Young Adult 03 medical and health sciences Age Distribution Diabetes mellitus Diabetes Mellitus medicine Humans Hemoglobin Sex Distribution Population Growth education Aged Retrospective Studies Type 1 diabetes business.industry Infant Newborn Infant Biology and Life Sciences Proteins Cell Biology medicine.disease Diagnostic medicine Diabetes Mellitus Type 1 Diabetes Mellitus Type 2 Age Groups Metabolic Disorders Population Groupings People and places business Demography |
| Zdroj: | PLoS Medicine PLoS Medicine, Vol 17, Iss 2, p e1003052 (2020) PLOS Medicine |
| ISSN: | 1549-1676 |
| Popis: | Background There is very limited data on the time trend of diabetes incidence in Asia. Using population-level data, we report the secular trend of the incidence of type 1 and type 2 diabetes in Hong Kong between 2002 and 2015. Methods and findings The Hong Kong Diabetes Surveillance Database hosts clinical information on people with diabetes receiving care under the Hong Kong Hospital Authority, a statutory body that governs all public hospitals and clinics. Sex-specific incidence rates were standardised to the age structure of the World Health Organization population. Joinpoint regression analysis was used to describe incidence trends. A total of 562,022 cases of incident diabetes (type 1 diabetes [n = 2,426]: mean age at diagnosis is 32.5 years, 48.4% men; type 2 diabetes [n = 559,596]: mean age at diagnosis is 61.8 years, 51.9% men) were included. Among people aged Andrw Oy Luk et al report the increasing incidence of Type 1 and 2 diabetes in Hong Kong. Author summary Why was this study done? Diabetes affects over 400 million people worldwide, and over half of the diabetes population comes from Asian countries. Most studies on the burden of diabetes in Asia reported the diabetes prevalence, i.e., the proportion of the population with disease, but few have considered diabetes incidence, i.e., the rate at which new cases have developed in the population. Knowledge of disease incidence informs how population exposure to risk factors has changed over time and is useful for projection of future prevalence. What did the researchers do and find? We identified 562,022 people with new-onset type 1 or type 2 diabetes occurring between 2002 and 2015 in the electronic medical record system of the Hong Kong Hospital Authority. We calculated the incidence rates of diabetes according to age categories and gender and analysed incidence trends over time. We found that the incidence of both type 1 and type 2 diabetes increased in children and adolescents (aged |
| Databáze: | OpenAIRE |
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