Daily fluctuation of levels of circulating cathodic antigen in urine of children infected with Schistosoma mansoni in Brazil

Autor: Ana Rabello, A.M. Deelder, N. Katz, M.M.A. Garcia, B. Gryseels, Márcia Nogueira Amorim, J. Disch, G.W. Krijger
Rok vydání: 1997
Předmět:
Zdroj: Transactions of the Royal Society of Tropical Medicine and Hygiene. 91:222-225
ISSN: 0035-9203
DOI: 10.1016/s0035-9203(97)90233-9
Popis: The fluctuation of circulating cathodic antigen (CCA) levels in urine was studied in 69 Brazilian school-children infected with Schistosoma mansoni and compared to egg counts. Faeces and urine samples were simultaneously collected at 7 times during a period of 2 weeks. CCA was determined by enzyme-linked immunosorbent assay and could be detected in 96% of the urine samples; the individual mean CCA level ranged from 609 to 350,700 pg/mL. 90% of the faecal samples contained S. mansoni eggs and the individual mean egg output ranged from 9 to 5510 eggs/g. The Spearman rank correlation coefficient between these individual means was 0.69. Kendall's coefficient of concordance (W) was 0.88 for CCA levels and 0.80 for egg counts.
Databáze: OpenAIRE