Cerebrospinal Fluid Dynamics in Patients with Pseudotumor Cerebri
| Autor: | Paul R. Cooper, W. K. Clark, C. W. Beyer, Frederick H Sklar, M. Ramanathan |
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| Rok vydání: | 1979 |
| Předmět: |
Adult
Male Adolescent Intracranial Pressure Pseudotumor cerebri Online Systems Lumbar Cerebrospinal fluid Humans Medicine Diagnosis Computer-Assisted Child Compartment (pharmacokinetics) Intracranial pressure Pseudotumor Cerebri business.industry Middle Aged medicine.disease Hydrocephalus Normal Pressure Pathophysiology Hydrocephalus Cerebrovascular Circulation Anesthesia Etiology Female Surgery Neurology (clinical) business |
| Zdroj: | Neurosurgery. 5:208-216 |
| ISSN: | 1524-4040 0148-396X |
| DOI: | 10.1227/00006123-197908000-00003 |
| Popis: | CSF dynamics were determined as a function of intracranial pressure in patients with pseudotumor cerebri. Servocontrolled variable rate lumbar infusions were used to determine net CSF-absorptive capacities and resting pressures in 10 patients; serial studies were done in 5 of the patients. Nearly all of the patients had abnormally low CSF-absorptive capacities. On the other hand, marked elevations in resting pressure were not a constant feature of the disease. Concurrent changes in the cerebrovascular bed could introduce errors into this manometric determination of CSF dynamics; the significance of this potential artifact is examined. The results of this study suggest that the CSF compartment may be of etiological importance in the pathophysiology of pseudotumor cerebri. |
| Databáze: | OpenAIRE |
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