Parathormone decline levels are better markers of symptomatic hypocalcemia following total thyroidectomy than parathormone alone
| Autor: | Vageesh Ayyar, Bharadhwaj Ravindhran, Belinda George, L N Mohan, Sendhil Rajan, Ganapathi Bantwal |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male endocrine system medicine.medical_specialty Time Factors endocrine system diseases medicine.medical_treatment Clinical Biochemistry Urology 03 medical and health sciences Postoperative Complications 0302 clinical medicine Drug Discovery Humans Medicine In patient 030212 general & internal medicine Morning Total thyroidectomy Hypocalcemia business.industry Biochemistry (medical) Thyroidectomy Middle Aged Intact pth Predictive value Parathyroid Hormone 030220 oncology & carcinogenesis Female business Biomarkers hormones hormone substitutes and hormone antagonists |
| Zdroj: | Biomarkers in Medicine. 14:1121-1126 |
| ISSN: | 1752-0371 1752-0363 |
| DOI: | 10.2217/bmm-2020-0218 |
| Popis: | Background: We aimed to assess the predictive value of the absolute and relative intact parathormone (iPTH) decline levels as reliable markers of postoperative hypocalcemia. Materials & methods: iPTH levels were measured 4 h after surgery and the following morning after surgery (postoperative day 1). iPTH, absolute iPTH decline (ΔPTH) and relative iPTH decline (ΔPTH%) were calculated and correlated with symptomatic hypocalcemia. Results: Of the 95 patients, 20% of patients (n = 19) developed symptomatic hypocalcemia. The ΔPTH (U = 206; p |
| Databáze: | OpenAIRE |
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