Stereoselective Synthesis of 2-(2-Hydroxyalkyl)piperidine Alkaloids Through Prins–Ritter Reaction

Autor: B. V. Subba Reddy, N. Siva Senkar Reddy, Y. Jayasudhan Reddy, Supriya Ghanty, J. S. Yadav
Rok vydání: 2014
Předmět:
DOI: 10.6084/m9.figshare.1025868
Popis: A stereoselective total synthesis of the 2-(2-hydroxyalkyl)piperidine alkaloids has been accomplished by a Prins–Ritter amidation sequence. Other steps involved in this synthesis are Jacobsen's hydrolytic kinetic resolution (HRK) and ring-closing metathesis (RCM).
Databáze: OpenAIRE