Research Progress on Human Endometrium Decidualization In vitro Cell Models
| Autor: | Wei Zhang, Hai-Yun Guan, Lu Wang, Zhi-Jing Tang |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Pregnancy
Stromal cell medicine.drug_class Female infertility Endometriosis Obstetrics and Gynecology Decidualization RC581-607 Biology RC648-665 medicine.disease Endometrium Diseases of the endocrine glands. Clinical endocrinology Andrology Menstruation medicine.anatomical_structure Reproductive Medicine Estrogen cyclic adenosine monophosphate decidualization endometrium estrogen in vitro cell model progestogen medicine Immunologic diseases. Allergy |
| Zdroj: | Reproductive and Developmental Medicine, Vol 5, Iss 2, Pp 119-127 (2021) |
| ISSN: | 2589-8728 |
| DOI: | 10.4103/2096-2924.320882 |
| Popis: | Decidualization is a special type of differentiation of endometrial stromal cells into secretory decidualized cells, which is closely related to the occurrence of menstruation and establishment of pregnancy. Decidualization abnormalities can cause female infertility and abortion, and the decidualization model in vitro is an important tool for studying relevant mechanisms. This article summarizes several in vitro decidualization models in recent research from three aspects, including the selection of model cells and culture systems, evaluation of decidualization markers, and induction schemes. These models can be appropriately selected and applied in specific endometrium-related disease models, such as endometriosis, recurrent pregnancy loss, and preeclampsia. |
| Databáze: | OpenAIRE |
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