Complex Virome in a Mesenteric Lymph Node from a Californian Sea Lion (Zalophus Californianus) with Polyserositis and Steatitis
| Autor: | Eric Delwart, Eda Altan, Frances M. D. Gulland, Terry R. Spraker, Xutao Deng, Yanpeng Li, Martha A. Delaney, Kathleen M. Colegrove, Elizabeth A. Wheeler |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Pathology Viral metagenomics perivascular Zalophus californianus viruses lcsh:QR1-502 Protoparvovirus granulomatous medicine.disease_cause lcsh:Microbiology California vasculitis 0403 veterinary science Parvovirus Rotavirus protoparvovirus Lymph node Serositis virome biology 04 agricultural and veterinary sciences steatitis Sea Lions polyserositis Infectious Diseases medicine.anatomical_structure Female Vasculitis medicine.medical_specialty food.ingredient 040301 veterinary sciences polyomavirus Animals Wild California sea lion Anelloviridae Article 03 medical and health sciences food Virology medicine Animals Human virome Inflammation biology.organism_classification medicine.disease 030104 developmental biology next-generation sequencing Lymph Nodes Metagenomics |
| Zdroj: | Viruses Volume 12 Issue 8 Viruses, Vol 12, Iss 793, p 793 (2020) |
| ISSN: | 1999-4915 |
| DOI: | 10.3390/v12080793 |
| Popis: | An emaciated subadult free-ranging California sea lion (Csl or Zalophus californianus) died following stranding with lesions similar to 11 other stranded animals characterized by chronic disseminated granulomatous inflammation with necrotizing steatitis and vasculitis, involving visceral adipose tissues in the thoracic and peritoneal cavities. Histologically, affected tissues had extensive accumulations of macrophages with perivascular lymphocytes, plasma cells, and fewer neutrophils. Using viral metagenomics on a mesenteric lymph node six mammalian viruses were identified consisting of novel parvovirus, polyomavirus, rotavirus, anellovirus, and previously described Csl adenovirus 1 and Csl bocavirus 4. The causal or contributory role of these viruses to the gross and histologic lesions of this sea lion remains to be determined. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
| Nepřihlášeným uživatelům se plný text nezobrazuje | K zobrazení výsledku je třeba se přihlásit. |