| Autor: |
Pruett, Jacob E., Everman, Steven J., Hoang, Ngoc H., Salau, Faridah, Taylor, Lucy C., Edwards, Kristin S., Hosler, Jonathan P., Huffman, Alexandra M., Romero, Damian G., Yanes Cardozo, Licy L. |
| Rok vydání: |
2022 |
| DOI: |
10.6084/m9.figshare.20521289 |
| Popis: |
Additional file 1: Figure S1. Representative adipose tissue images. Representative histological images in (A) subcutaneous, (B) retroperitoneal, and (C) mesenteric white adipose tissue. Control and PCOS rats were treated with and without empagliflozin (EMPA). Images were taken at 40× magnification. Figure S2. Effect of EMPA on protein expression on antioxidant enzymes in retroperitoneal white adipose tissue in PCOS. Effect of EMPA on retroperitoneal white adipose tissue (WAT) protein expression of (A) cytosolic superoxide dismutase (SOD1, ~ 18 kDa), (B) mitochondrial superoxide dismutase (SOD2, ~ 22 kDa), and (C) catalase (~ 60 kDa) after 3 weeks of EMPA treatment. Data were normalized by total protein content (TPC). Data are expressed as mean ± SEM and were analyzed by two-way ANOVA followed by Tukey post hoc tests. No significant interaction was observed by two-way ANOVA. n = 4–5 per group. Figure S3. Effect of EMPA on protein expression on antioxidant enzymes in mesenteric white adipose tissue in PCOS. Effect of EMPA on mesenteric white adipose tissue (WAT) protein expression of (A) cytosolic superoxide dismutase (SOD1, ~ 18 kDa), (B) mitochondrial superoxide dismutase (SOD2, ~ 22 kDa), and (C) catalase (~ 60 kDa) after 3 weeks of EMPA treatment. Data were normalized by total protein content (TPC). Data are expressed as mean ± SEM and were analyzed by two-way ANOVA followed by Tukey post hoc tests. No significant interaction was observed by two-way ANOVA. n = 4 per group. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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