Prevalence and risk factors of prolonged corrected QT interval in general Chinese population
| Autor: | Guowei Pan, Zhao Li, Xiaofan Guo, Shasha Yu, Liang Guo, Yonghong Zhang, Yingxian Sun, Liqiang Zheng, Hongmei Yang, Qun Ma, Lu Zou |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty lcsh:Diseases of the circulatory (Cardiovascular) system China Long QT syndrome Population Action Potentials Comorbidity Rural Health 030204 cardiovascular system & hematology Logistic regression QT interval Risk Assessment 03 medical and health sciences 0302 clinical medicine Sex Factors Heart Rate Internal medicine Diabetes mellitus medicine Prevalence Humans 030212 general & internal medicine cardiovascular diseases education Disease burden Abdominal obesity Aged education.field_of_study business.industry Confounding Age Factors Middle Aged medicine.disease Prognosis Health Surveys Long QT Syndrome Risk factors lcsh:RC666-701 Female medicine.symptom Cardiology and Cardiovascular Medicine business Research Article |
| Zdroj: | BMC Cardiovascular Disorders BMC Cardiovascular Disorders, Vol 19, Iss 1, Pp 1-10 (2019) |
| ISSN: | 1471-2261 |
| Popis: | Background Corrected QT (QTc) interval has been correlated with total and CVD mortality. Although much is known about the relation between prolonged QTc interval and clinical outcome, there is no information on the prevalence and specific risk factors of QTc prolongation in general Chinese population. We evaluated the prevalence of prolonged QTc interval and its risk factors in general Chinese population, aiming to fill in the gaps in the literature and provide evidence for potential CVD risk prediction and disease burden estimate in community. Methods A population-based survey was conducted on 11,209 participants over the age of 35 in rural areas of Liaoning Province from 2012 to 2013. Twelve-lead ECGs and automatic analysis were performed on all participants. Logistic regression adjustments were made by using the Bazett’s formula to correlate specific risk factors with prolonged QTc intervals (> 440 ms) for potential confounders. Results The overall prevalence of prolonged QTc interval was 31.6%. The prevalence increased significantly with age (24.1% among those aged 35–44 years; 28.3%, 45–54 years; 35.2%, 55–64 years; 43.4%, ≥65 years, P P Conclusions The prevalence of prolonged QTc interval was relatively high in general Chinese population and listed relevant factors, which would help identify patients at risk in pre-clinical prevention and provide evidence for estimating potential CVD burden and making management strategies in community. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink