Technical note: Novel use of recombinant tissue plasminogen activator for the evacuation of an acute extensive spinal epidural haematoma in a patient with coagulopathy
| Autor: | Kieron J. Sweeney, Stavros Koustais, Ciaran Bolger |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
business.industry medicine.medical_treatment Laminectomy General Medicine medicine.disease Spinal column Surgery 03 medical and health sciences Myelopathy 0302 clinical medicine 030220 oncology & carcinogenesis medicine Coagulopathy cardiovascular diseases Neurology (clinical) Neurosurgery Recombinant tissue plasminogen activator business Spinal epidural haematoma 030217 neurology & neurosurgery Fixation (histology) |
| Zdroj: | British Journal of Neurosurgery. :1-4 |
| ISSN: | 1360-046X 0268-8697 |
| DOI: | 10.1080/02688697.2020.1773395 |
| Popis: | Spontaneous extensive spinal epidural haematoma poses a unique challenge for the neurosurgeon. Performing extensive laminectomies to remove all of the compressive haematoma can destabilise the patient's spinal column, which may require fixation. This is further complicated in patients with significant coagulopathy. We present a novel use of recombinant tissue plasminogen activator (rt-PA) in a patient with therapeutic coagulopathy, presenting with myelopathy secondary to an acute extensive spinal epidural haematoma. To the best of our knowledge, this is the first case of acute multilevel spinal epidural haematoma that has been successfully evacuated via single level laminectomy and topically applied rt-PA. |
| Databáze: | OpenAIRE |
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