Reducing blood loss after total knee replacement
| Autor: | Edwin P. Su, H. Osoria, Denis Nam, Mark P. Figgie, K. R. Reinhardt, M. A. Alexiades |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
Male medicine.medical_specialty Blood transfusion medicine.medical_treatment Total knee replacement Blood Loss Surgical Range of movement Blood volume Fibrin Tissue Adhesive Fibrin Postoperative Complications Blood loss medicine Humans Blood Transfusion Orthopedics and Sports Medicine Multi unit Range of Motion Articular Arthroplasty Replacement Knee Aged Aged 80 and over Blood Volume biology business.industry Sealant Middle Aged Surgery Treatment Outcome Anesthesia biology.protein Female business |
| Zdroj: | The Bone & Joint Journal. :135-139 |
| ISSN: | 2049-4408 2049-4394 |
| DOI: | 10.1302/0301-620x.95b11.32904 |
| Popis: | Blood loss during total knee replacement (TKR) remains a significant concern. In this study, 114 patients underwent TKR, and were divided into two groups based on whether they received a new generation fibrin sealant intra-operatively, or a local infiltration containing adrenaline. Groups were then compared for mean calculated total blood volume (TBV) loss, transfusion rates, and knee range of movement. Mean TBV loss was similar between groups: fibrin sealant mean was 705 ml (281 to 1744), local adrenaline mean was 712 ml (261 to 2308) (p = 0.929). Overall, significantly fewer units of blood were transfused in the fibrin sealant group (seven units) compared with the local adrenaline group (15 units) (p = 0.0479). Per patient transfused, significantly fewer units of blood were transfused in the fibrin sealant group (1.0 units) compared with the local adrenaline group (1.67 units) (p = 0.027), suggesting that the fibrin sealant may reduce the need for multiple unit transfusions. Knee range of movement was similar between groups. From our results, it appears that application of this newer fibrin sealant results in blood loss and transfusion rates that are low and similar to previously applied fibrin sealants. Cite this article: Bone Joint J 2013;95-B, Supple A:135–9. |
| Databáze: | OpenAIRE |
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