Antimicrobial efficacy of silver diamine fluoride in comparison to photodynamic therapy and chlorhexidine on canal disinfection and bond strength to radicular dentin
Autor: | Ahmed M Maawadh, Fahim Vohra, Thamer Almohareb, Eisha Abrar, Mustafa Naseem, Tariq Abduljabbar, Mohammed Q. AlRifaiy, Qaiser Ali Baig |
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Rok vydání: | 2020 |
Předmět: |
Sodium Hypochlorite
Root canal medicine.medical_treatment 030303 biophysics Biophysics Dentistry Photodynamic therapy Dermatology 030207 dermatology & venereal diseases 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine medicine Pharmacology (medical) Silver diamine fluoride Fluorides Topical 0303 health sciences Photosensitizing Agents biology Root Canal Irrigants Chemistry business.industry Bond strength Chlorhexidine Silver Compounds Gutta-percha biology.organism_classification Antimicrobial Disinfection Quaternary Ammonium Compounds medicine.anatomical_structure Oncology Photochemotherapy Sodium hypochlorite Dentin Dental Pulp Cavity business Root Canal Preparation medicine.drug |
Zdroj: | Photodiagnosis and photodynamic therapy. 32 |
ISSN: | 1873-1597 |
Popis: | Aim To assess the antimicrobial efficacy of Silver diamine fluoride (SDF), Sodium hypochlorite (NaOCl), Chlorhexidine (CHX) and Photodynamic therapy (PDT) in radicular dentin and subsequent bond strength of Fiber reinforced composite post (FRCP) to radicular dentin. Material and methods Forty extracted premolars were disinfected and decoronated up-to cement-o-enamel junction (CEJ). Canals were instrumented using crown-down technique, dried and filled with gutta percha. Post space was prepared with the help of peso reamers and inoculated with E. faecalis. Samples were randomly allocated into four groups based on chemical irrigation (n = 10). Group 1, canal disinfected with (PDT, MB), group 2 (5.25 % NaOCl +17 % EDTA), group 3 (3.8 % SDF) and group 4 (CHX). Specimens were tested with confocal laser scanning microscopy analysis (CLSM) to confirm the presence of E. faecalis. Fibre post were luted in root canal and sectioned at three levels (apical, middle and coronal). Push-out test was performed and failure analysis of debonded surfaces was evaluated using stereomicroscope. Live and dead cells after exposure were calculated in percentage. One-way analysis of variance (ANOVA) assessed the means and standard deviations of extrusion bond strength (EBS). Tukey multiple comparison tests was used to compare means of bond strength (p = 0.05). Results The maximum antimicrobial efficacy against E. faecalis was observed in group 2 which included canal disinfected with 5.25 % NaOCl and 17 % EDTA (64.41 ± 1.22). Similarly, CHX showed lowest effectiveness as canal irrigant against E.faecalis (58.29 ± 2.41). Intragroup comparison revealed highest bond strength for group 2 at all three level. Similarly, the lowest EBS was found in CHX group. Inter-group comparison confirmed comparable EBS at all root levels (apical, middle and coronal) for group 2 and group 3 (p > 0.05). Conclusion Radicular dentin treated with 5.25 % NaOCl and 17 % EDTA displayed highest antimicrobial and bond strength scores. SDF and PDT can potentially be used in canal irrigation. |
Databáze: | OpenAIRE |
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