Physical activity modulates arterial stiffness in children with congenital heart disease: A CHAMPS cohort study
| Autor: | Shonah Runalls, Ashok Kakadekar, Stephanie Fusnik, Kristi D. Wright, Charissa Pockett, Scott Pharis, Michael K. Stickland, Timothy J. Bradley, Natasha G. Boyes, Elizabeth Hogeweide, Mark J. Haykowsky, Corey R. Tomczak, Chantelle L. Baril, Josie T.J. Fries, Marta C Erlandson |
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| Rok vydání: | 2018 |
| Předmět: |
Heart Defects
Congenital Male Applanation tonometry medicine.medical_specialty Heart disease Physical activity Blood Pressure Pulse Wave Analysis 030204 cardiovascular system & hematology Electrocardiography 03 medical and health sciences Vascular Stiffness 0302 clinical medicine Internal medicine medicine Humans Step count Radiology Nuclear Medicine and imaging 030212 general & internal medicine Child Exercise Pulse wave velocity business.industry General Medicine medicine.disease Pediatrics Perinatology and Child Health Exercise Test Cardiology Arterial stiffness Female Surgery Analysis of variance Cardiology and Cardiovascular Medicine business Cohort study |
| Zdroj: | Congenital Heart Disease. 13:578-583 |
| ISSN: | 1747-079X |
| DOI: | 10.1111/chd.12614 |
| Popis: | Children with congenital heart disease are at risk for developing increased arterial stiffness and this may be modulated by physical activity.To compare arterial stiffness in high- and low-physically active children with congenital heart disease and healthy age- and sex-matched controls.Seventeen children with congenital heart disease (12 ± 2 years; females = 9), grouped by low- and high-physical activity levels from accelerometry step count values, and 20 matched controls (11 ± 3 years; females = 9) were studied.Carotid-radial pulse wave velocity was assessed with applanation tonometry to determine arterial stiffness. Body composition and 6-min walk test measures were performed. Data were analyzed using analysis of variance and multiple regression. Significance was P .05.Arterial stiffness was increased in low-physically active children with congenital heart disease (9.79 ± 0.97 m/s) compared to high-physically active children with congenital heart disease (7.88 ± 0.71 m/s; P = .002) and healthy-matched controls (8.67 ± 1.28 m/s; P = .015). There were no differences in body composition measures between groups (all P .05), but 6-min walk test distance was less in both congenital heart disease groups (high-physically active: 514 ± 40 m; low-physically active: 539 ± 49 m) versus controls (605 ± 79 m; all P .05). Average daily step count significantly predicted arterial stiffness in children with congenital heart disease (RLow-physically active children with congenital heart disease have increased arterial stiffness compared to high-physically active children with congenital heart disease and healthy-matched controls. Regular physical activity in children with congenital heart disease may modulate arterial stiffness. |
| Databáze: | OpenAIRE |
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