Vitamin D Status and Its Relationship with Metabolic Markers in Persons with Obesity and Type 2 Diabetes in the UAE: A Cross-Sectional Study
| Autor: | Sijomol Skaria, Solafa M. Ahmed, Amena Sadiya, Salah Abusnana |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Adult
Blood Glucose Male medicine.medical_specialty Waist Article Subject Endocrinology Diabetes and Metabolism Population Parathyroid hormone United Arab Emirates Type 2 diabetes lcsh:Diseases of the endocrine glands. Clinical endocrinology vitamin D deficiency Body Mass Index Endocrinology Internal medicine Vitamin D and neurology Prevalence Medicine Humans Obesity Vitamin D education Glycemic Adiposity education.field_of_study lcsh:RC648-665 business.industry Fasting Middle Aged medicine.disease Vitamin D Deficiency Cross-Sectional Studies Diabetes Mellitus Type 2 Calcium Female Waist Circumference business Body mass index Biomarkers Research Article |
| Zdroj: | Journal of Diabetes Research, Vol 2014 (2014) Journal of Diabetes Research |
| ISSN: | 2314-6745 |
| DOI: | 10.1155/2014/869307 |
| Popis: | Aim.To report vitamin D status and its impact on metabolic parameters in people in the United Arab Emirates with obesity and type 2 diabetes (T2D).Methodology.This cross-sectional study included 309 individuals with obesity and T2D who were randomly selected based on study criteria. Serum concentrations of 25-hydroxy vitamin D (s-25(OH)D), calcium, phosphorus, parathyroid hormone, alkaline phosphatase, glycemic profile, and cardiometabolic parameters were assessed in fasting blood samples, and anthropometric measurements were recorded.Results.Vitamin D deficiency (s-25(OH)D < 50 nmol/L) was observed in 83.2% of the participants, with a mean s-25(OH)D of 33.8 ± 20.3 nmol/L. Serum 25(OH)D correlated negatively (P<0.01) with body mass index, fat mass, waist circumference, parathyroid hormone, alkaline phosphatase, triglycerides, LDL-cholesterol, and apolipoprotein B and positively (P<0.01) with age and calcium concentration. Waist circumference was the main predictor of s-25(OH)D status. There was no significant association between serum 25(OH)D and glycemic profile.Conclusion.There is an overwhelming prevalence of vitamin D deficiency in our sample of the Emirati population with obesity and T2D. Association of s-25(OH)D with body mass index, waist circumference, fat mass, markers of calcium homeostasis and cardiometabolic parameters suggests a role of vitamin D in the development of cardiometabolic disease-related process. |
| Databáze: | OpenAIRE |
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