Morning Blood Glucose Determination in the Monitoring of Metabolic Control in Type 2 Elderly Diabetic Cases Treated by Oral Hypoglycemic Agents
| Autor: | Keiko Sasai, Yumiko Ajiro, K Ohba, T. Suzuki, H Nnakano, Kyoji Okazaki, S Satoh, Y Matsuura, Hitoshi Koibuchi, S Mmetori |
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| Rok vydání: | 1999 |
| Předmět: |
Male
medicine.medical_specialty Administration Oral Blood Glucose Self-Monitoring Internal medicine Diabetes mellitus medicine Humans Hypoglycemic Agents In patient Circadian rhythm Aged Morning business.industry Fasting medicine.disease Circadian Rhythm Sulfonylurea Compounds Endocrinology Diabetes Mellitus Type 2 Before Breakfast Metabolic control analysis Oral hypoglycemic agents Female Geriatrics and Gerontology business |
| Zdroj: | Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics. 36:122-127 |
| ISSN: | 0300-9173 |
| DOI: | 10.3143/geriatrics.36.122 |
| Popis: | Daily blood glucose profiles were measured in 163 Type 2 elderly diabetic cases to evaluate whether a fasting (before breakfast) or a post-prandial (after breakfast) blood glucose concentration is able to predict blood glucose values throughout the day. In the diet-treated alone group (n = 61), the percentage of daily blood glucose profiles having plasma glucose values less than the 08:00 hours (before breakfast) value were as follows: 59.0%, 32.8%, 59.0%, and 55.7% at 18.00 (before supper), 24.00, 03.00, 06.00 hours, respectively. In group treated by oral hypoglycemic agents (OHA) (n = 102), these were as follows: 45.1%, 26.5%, 52.9%, and 67.6%, respectively. In the OHA group, the mean plasma glucose value at 08:00 hours was significantly higher in patients with the lowest plasma glucose levels between 60-79 mg/dl than in patients with these levels between 80-99 mg/dl (103.7 +/- 19.6 vs 118.7 +/- 16.9 mg/dl, p < 0.01), but that at 10:00 hours was similar in the two groups (218.8 +/- 43.9 vs 214.5 +/- 40.1 mg/dl). In patients with lowest plasma glucose levels of between 60-99 mg/dl, the 08:00 hours value correlated positively with that of 24:00 (r = 0.40), 03.00 (r = 0.53), and the 06.00 hours value (r = 0.69), but no correlation was observed with the 18.00 hours value. On the other hand, the 10:00 hours value was not associated with these time-points values. Our results reveal that before breakfast plasma glucose values are more predictive of low blood glucose values in the night during sleep than after-breakfast blood glucose values, but do not predict low blood glucose values before supper in patients on OHA. |
| Databáze: | OpenAIRE |
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