Effective vitamin B12 treatment can reduce serum antigastric parietal cell antibody titer in patients with oral mucosal disease
| Autor: | Hsin-Ming Chen, Shih-Jung Cheng, Andy Sun, Julia Yu Fong Chang, Chun-Pin Chiang, Yi Ping Wang |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male burning mouth syndrome medicine.medical_specialty Glossitis antigastric parietal cell antibody hematinic deficiency Taiwan Gastroenterology Young Adult 03 medical and health sciences 0302 clinical medicine Parietal Cells Gastric Internal medicine medicine Humans Vitamin B12 Hematinic oral mucosal disease Aged Autoantibodies Aged 80 and over Medicine(all) lcsh:R5-920 vitamin B12 treatment business.industry atrophic glossitis Case-control study Autoantibody General Medicine Middle Aged Burning mouth syndrome medicine.disease Vitamin B 12 Titer Endocrinology Case-Control Studies 030220 oncology & carcinogenesis Vitamin B Complex Hematinics Female 030211 gastroenterology & hepatology medicine.symptom Intramuscular injection business lcsh:Medicine (General) |
| Zdroj: | Journal of the Formosan Medical Association, Vol 115, Iss 10, Pp 837-844 (2016) |
| ISSN: | 0929-6646 |
| DOI: | 10.1016/j.jfma.2016.05.003 |
| Popis: | Background/purposePatients with serum antigastric parietal cell antibody (GPCA) positivity may have vitamin B12 deficiency and some oral symptoms. This study assessed the changes of serum GPCA titer in GPCA-positive patients after effective vitamin B12 treatment.MethodsTwo hundred and ten GPCA-positive oral mucosal disease patients became oral symptom free (complete response) after 1.0–67.1 months of treatment with regular and continuous intramuscular injection of vitamin B12 once per week. The changes of serum GPCA titers after treatment were evaluated in these 210 patients.ResultsWe found a significant drop of the GPCA positive rate from 100% to 42.9% in our 210 complete response patients after effective vitamin B12 treatment (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|