The influence of ligand on the tissue distribution of carrier free 111In in the rat
| Autor: | S.W. Gunasekera, M.L. Thakur, M.V. Merrick, A.D. Nunn |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
Carrier free
Porphyrins Ionic bonding Acetates Kidney Ligands Bleomycin Indium Excretion chemistry.chemical_compound Chlorides Bone Marrow Animals Distribution (pharmacology) Radiology Nuclear Medicine and imaging Chelation Citrates Tissue distribution Lung Edetic Acid Skin Radioisotopes Chromatography Chemistry Ligand Muscles Rats Inbred Strains Rats carbohydrates (lipids) Liver Lactates Spleen |
| Zdroj: | International Journal of Nuclear Medicine and Biology. 2:45-48 |
| ISSN: | 0047-0740 |
| Popis: | The distribution of radioactivity in the rat has been studied following the administration of ionic 111In CI3, and of chelates of 111In with lactic, citric and acetic acids, HEDTA, bleomycin and TPP. The ionic form is excreted least, and HEDTA and bleomycin most, the others being intermediate. Allowing for differences in excretion there is no significant difference in the distribution in normal tissues of the retained part of any of the compounds studied, with the exception of TPP which gave high levels in the liver. |
| Databáze: | OpenAIRE |
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