Клінічна оцінка характеристик сучасної панкреатичної інфекції в обґрунтуванні лікувальної тактики при гострому панкреатиті
| Autor: | D. V. Andriushchenko, V. P. Andriushchenko, М. Yu. Nychytaylo, V. А. Mahlovanyi |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
biology business.industry medicine.drug_class Aerobic bacteria Antibiotics lcsh:Surgery lcsh:RD1-811 General Medicine Disease biology.organism_classification medicine.disease Enterobacter aerogenes Gastroenterology гострий панкреатит характеристики інфекційного чинника клінічне значення Internal medicine Medicine Acute pancreatitis Clinical significance business Anaerobic exercise Bacteria |
| Zdroj: | Клінічна хірургія, Vol 85, Iss 5, Pp 21-24 (2018) |
| ISSN: | 2522-1396 0023-2130 |
| DOI: | 10.26779/2522-1396.2018.05.21 |
| Popis: | Objective. Studying of characteristics of modern infective causative agent (ICA) in an acute pancreatitis (AP) and analysis of their clinical significance. Маterials and methods. In total 147 bacteriological investigations were done in patients, suffering AP, using procedures of aerobic and anaerobic culturing of the material. Results. There was suggested, that ICA is presented by microflora with domination of aerobic bacteria in form of monoculture (37% of observations) and аеrobic-аnaerobic аssociations (39%) with gram-negative sign (56%), different tropism of bacteria for pathomorphological substrates and stability for existing associations (57%). Enterococcus spp. and Enterobacter aerogenes have appeared as «microorganisms-іndicators» for the anaerobic microflora presence. There was established, that ІCA is joining in early (17%), as well as in late (31%) terms of the disease. Peculiarities of the antibiotics application in regime of preventive and etiotropic therapy were noted. The ІCA signs were delineated, which constitute predictors of the AP course severity. Conclusion. ICA in AP includes predominantly enterobacteria and anaerobic microflora in a form of monoculture and aerobic-anaerobic associations. The pancreatic tissues infectioning, early input of ІCA, domination of aerobic-anaerobic microflora and its gram-negative belonging constitute criteria for estimation of the disease course severity. Preventive antibioticotherapy promotes the aseptic inflammation (68%) preservation. In postoperative period antibiotics is expedient to prescribe in regime of etiotropic antibioticotherapy. |
| Databáze: | OpenAIRE |
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