Sickle cell trait: a cause of abdominal pain and pulmonary embolism
| Autor: | Gabriela Monzoni, Ayelén Tarditi Barra, Aldo H. Tabares, Carolina Villegas, Emanuel José Saad |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Abdominal pain medicine.medical_treatment Population lcsh:Medicine Gastroenterology Sickle Cell Trait Laparotomy Internal medicine medicine Humans Splenic Infarction education lcsh:R5-920 education.field_of_study Lupus anticoagulant Sickle cell trait business.industry lcsh:R General Medicine medicine.disease Sickle cell anemia Pulmonary embolism Abdominal Pain Splenic infarction lupus coagulation inhibitor medicine.symptom lcsh:Medicine (General) business Pulmonary Embolism Tomography X-Ray Computed |
| Zdroj: | Revista de la Facultad de Ciencias Médicas de Córdoba, Vol 77, Iss 4 (2020) |
| ISSN: | 1853-0605 |
| Popis: | Introduction: Sickle cell trait (SCT) is a rare and underdiagnosed disorder in the Argentinian population. In this condition, individuals carry the mutation of the HbS gene in one of the two beta-globin genes. In general, SCT does not present with the typical manifestations of sickle cell anemia. However, under certain circumstances, some clinical characteristics of the disease may develop. Methods: We discussed the case of a 39-Year old man who presented with persistent abdominal pain of unknown origin after traveling to a high-altitude place. He underwent laparotomy without a definite diagnosis. After that, the patient developed signs of splenic infarction and pulmonary thromboembolism that were confirmed by computed tomography. Results: A sickling test was positive, and a hemoglobin electrophoresis revealed an abnormal fraction at the HbS level. In this context a diagnosis of SCT was made. Additional, tests revealed a strongly positive lupus anticoagulant. Conclusion: SCT presentation as abdominal pain and thromboembolic disease in adult patients after exposure to high altitudes is a rarely suspected diagnosis. |
| Databáze: | OpenAIRE |
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