| Autor: |
Jiaao, Lu, Muneeb, Zia, Matthew J, Williams, Amanda L, Jacob, Bryce, Chung, Samuel J, Sober, Muhannad S, Bakir |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Annu Int Conf IEEE Eng Med Biol Soc |
| Popis: |
High signal-to-noise ratio (SNR) electromyography (EMG) recordings are essential for identifying and analyzing single motor unit activity. While high-density electrodes allow for greater spatial resolution, the smaller electrode area translates to a higher impedance and lower SNR. In this study, we developed an implantable and flexible 3D microelectrode array (MEA) with low impedance that enables high-quality EMG recording. With polyimide micro-cones realized by standard photolithography process and PEDOT:PSS coating, this design can increase effective surface area by up to 250% and significantly improve electrical performance for electrode sites with various geometric surface areas, where the electrode impedance is at most improved by 99.3%. Acute EMG activity from mice was recorded by implanting the electrodes in vivo, and we were able to detect multiple individual motor units simultaneously and with high resolution (SNR ≫ 100). The charge storage capacity was measured to be 34.2 mC/cm2, indicating suitability of the electrodes for stimulation applications as well. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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