TOXICOLOGICAL EVALUATION OF THE PLANT Xanthium strumarium IN PIGS IN ZIMBABWE
| Autor: | C. Masvingwe, M. Mavenyengwa |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1998 |
| Předmět: |
Zimbabwe
Abdominal pain Pathology medicine.medical_specialty biology Xanthium strumarium toxicosis hepatocyte necrosis Cardiac muscle Toxicology Sudden death Fibrin medicine.anatomical_structure striated muscle fiber and renal tubular degeneration Ascites medicine biology.protein Vomiting Ingestion medicine.symptom Pathological |
| Zdroj: | Journal of Venomous Animals and Toxins, Volume: 4, Issue: 2, Pages: 113-119, Published: 1998 |
| Popis: | Major clinical signs were depression, vomiting, abdominal pain, weakness, recumbency, paddling convulsions terminating in death from 6 to 96 hours after ingestion. Gross pathological findings included ascites with fibrin strands, enlarged, congested and friable livers with accentuation of lobulation on the capsule. Microscopically, acute hepatic congestion and hemorrhage, centrilobular hepatocyte necrosis, with occasional binucleation together with discoid lysis of skeletal and cardiac muscle fibers were remarkable changes. Binucleation of hepatocytes and degenerative changes in active muscles have not been reported before in relation to cocklebur plant toxicosis. These findings suggest that X. strumarium is a potential cause of sudden death in pigs extensively reared in Zimbabwe. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|